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KMID : 0858520150190010056
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Journal of the Korean Society of Magnetic Resonance in Medicine
2015 Volume.19 No. 1 p.56 ~ p.61
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MR Imaging Findings of Tamoxifen-associated Uterine Adenosarcoma: Report of Two Cases
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Choi Soo-Yeon
Sung Deuk-Jae
Han Na-Yeon
Park Beom-Jin
Kim Min-Ju
Sim Ki-Choon
Cho Sung-Bum
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Abstract
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Adenosarcoma of the uterus is a rare biphasic tumor containing benign glandular epithelial and malignant mesenchymal components. The tumor has been reported to be associated with antiestrogen therapy, particularly tamoxifen, but there have been a few case reports with MRI. We present two cases of MRI findings of uterine adenosarcoma after antiestrogen therapy, tamoxifen and toremifene in breast cancer patients. The tumor presents as a large polypoid mass occupying the endometrial cavity, and may protrude into the vagina. On MRI, the tumor typically shows solid components with scattered small cysts and heterogeneous enhancement. These findings are not significantly different from conventional adenosarcoma.
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KEYWORD
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Magnetic resonance imaging, Uterine adenosarcoma, Estrogen receptor modulators, Breast cancer
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